Many of us have faced such type of problem when our hard drives don't open after double clicking on them. It can happen for Virus attack on your PC. Many viruses creates autorun.inf file on the root of drives which executes a selected virus file, so the drive can not open or opens with infecting your PC.  Here is a simple solution, that how you can remove the autorun.inf file and get rid of this problem. 

 

1:-Press Start >>Run  >> Type cmd

2:-Select hard drive path name as D or E ete.